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New Research Highlight: Validating the VITROCELL Cloud Alpha MOVE
We’re proud to see our technology featured in the latest poster by Matthew Sheavyn & Victoria Pack from Dstl. Dstl is one of the principal government organisations dedicated to science and technology in the defence and security field, located in Porton Down, UK. Their work underscores the importance of characterizing and validating advanced in vitro inhalation exposure systems before deploying them in research projects. In their study, the VITROCELL Cloud Alpha MOVE was rigorously tested and demonstrated: ✅ A low variation in delivered dose across all 24 positions (±6%) ✅ High deposition efficiency: 75.3% (determined via fluorescence-based FNA assay) and 72.4% (measured using an integrated QCM) ✅ A clear, stepwise…
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Organ-on-Chip (OoC) Exposure – From Gas to Dry Powders in One Complete Solution
Vitrocell and AlveoliX set the benchmark in Organ-on-chip technology, delivering complete aerosol capability on chip for lung, skin and eye exposure. The AlveoliX Barrier-on-chip, especially the breathable lung-on-chip model, enables unmatched flexibility for inhalation research at the air-liquid interface. Vitrocell’s advanced exposure systems accommodate all aerosol types for the AlveoliX AX12 – from gas and vapor phases to liquid aerosols and dry powders – enabling realistic, precise, and reproducible testing conditions. This versatility empowers researchers to explore the full range of respiratory exposure scenarios under human-relevant conditions, from environmental pollutants, over combustion aerosols, to cutting-edge therapeutics. Are you interested? Discover the options here: Product News Organ-on-Chip Exposure Über die VITROCELL…
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New Application Note: Precise Dry Powder Analysis with VITROCELL sQCM 12
Tired of unreliable QCM results when working with dry particles? Irregular deposition and weak bonding are a common challenge in nanoparticle research. That’s why we developed the new VITROCELL Dry Powder Kit – optimized for use with PowderX! This innovative kit ensures stable and reproducible dry powder deposition, enabling precise dose monitoring with the VITROCELL sQCM 12 sensor. ✅ Stable & reproducible dry powder deposition measurement ✅ User-friendly post-processing procedure for seamless integration ✅ Integrated data analysis in VITROCELL Monitor Software Easy and precise dosimetry: Post-treatment stabilizes particles into a rigid layer, enabling accurate mass deposition calculations via Sauerbrey’s equation. A one-time calibration allows direct dosimetry within PowderX. Important to…
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Meet Navetta: New Approach to Safety Testing of Drugs and Particles
Navetta offers an innovative solution for safety testing of drugs and particles at the Air-Liquid Interface. What makes Navetta different? This novel exposure system uses smooth, low-speed horizontal airflow combined with an electrical field that enhances particle deposition directly onto lung cells. Temperature and humidity remain controlled, keeping cells viable throughout exposure. Key advantages High Deposition Efficiency – Charged particles are accelerated toward cells via electric field, dramatically increasing deposition rates Uniform Distribution – Homogeneous electric field ensures even particle coverage across the exposure area Ultrafine & Nanoparticle Ready – Strong electrostatic forces capture the smallest particles that would otherwise remain suspended Seamless Integration – Successfully couples with Preciseinhale® for…
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Novel Groundbreaking technology for real-time tracking of particle deposition
We are proud to share the first publication introducing CalorQuanti as a groundbreaking technology for real-time tracking of particle deposition on lung cells. Researchers from the BioNanomaterials group at the Adolphe Merkle Institute have successfully validated the novel CalorQuanti System, developed in collaboration with NanoLockin and VITROCELL Systems GmbH. The Cloud Alpha/CalorQuanti platform integrates advanced aerosol exposure technology with lock-in thermography, enabling precise, non-destructive monitoring of particle deposition at the air-liquid interface. This innovative system closely replicates real-life inhalation conditions, allowing researchers to quantify particle deposition in real time and assess biological responses in the same living cell cultures. This advance marks a significant step toward more accurate toxicity assessments…
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cellQART – the ideal inserts for your VITROCELL Exposure System:
It is our pleasure to introduce a selection of cellQART cell culture inserts now available for purchase from VITROCELL. Outstanding material quality, innovative design, optimized performance, exceptional customer support, and competitive pricing make cellQART inserts the ideal choice for experiments at the air-liquid interface: 1. Material Quality: cellQART inserts feature highly specialized membranes designed to enhance cell growth and to achieve highest reproducibility. Uniformly distributed pores ensure precise and reliable results, particularly essential for delicate cell culture experiments. 2. Design Innovation: cellQART inserts provide unique design features tailored to maximize experimental efficiency and improve user experience. 3. Optimized Performance: These inserts are specifically engineered for specialized research applications, including barrier integrity assessments, transport studies, and co-culture…
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Customer Report: National Center for Scientific Research ‘Demokritos’ in Greece about inhalation research with the ESSENTIALS Exposure System
The National Center for Scientific Research “Demokritos” – Institute of Nanoscience and Nanotechnology recently welcomed Greece’s first VITROCELL installation. To ensure a seamless start, the VITROCELL Systems team was on-site in Athens for the installation and hands-on training. The research team specializes in nanostructured materials with advanced functionalities, including catalytic materials, antimicrobial nanomaterials, pollutant abatement solutions, multifunctional coatings, and targeted drug delivery systems for cancer treatment. Until now, the team primarily relied on submerged lung cell cultures for nanotoxicity studies. With the introduction of the VITROCELL ESSENTIALS system, they can now conduct Air-Liquid Interface (ALI) exposure, bringing their research closer to real-world respiratory conditions and significantly enhancing toxicological relevance. Exclusive…
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Application areas and exposure principles for in vitro lung cell research
Explore Application Areas and Exposure Principles for in vitro Inhalation Research VITROCELL® devices are designed to evaluate the potential health risks of inhalable substances without relying on laboratory animals. These systems expose lung cells at the air-liquid interface, simulating real-world inhalation conditions. A newly released video presentation highlights key in vitro exposure systems designed for all types of aerosols, including: Gases, complex mixtures, and particles in continuous flow Liquids and suspensions via single droplet sedimentation Dry powders in minimal quantities Watch the video on our YouTube channel Exposure Systems for in vitro inhalation research Comprehensive Cell Exposure Systems VITROCELL® offers a variety of advanced cell exposure systems capable of directly…
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Collaborative Breakthrough in Lung-on-Chip Technology
Collaborative Breakthrough in Lung-on-Chip Technology: AlveoliX, Vitrocell, University of Bern and Helmholtz Institute for Pharmaceutical Research Saarland Drive Advances in Human Respiratory Research AlveoliX, in collaboration with Vitrocell Systems, the University of Bern, and the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) is proud to announce the publication of a landmark study in Bioengineering & Translational Medicine. The study, titled “A stretchable human lung-on-chip model of alveolar inflammation for evaluating anti-inflammatory drug response”, was made possible through the AIM-4-Doc grant from Eurostars. This study demonstrates how this Lung-on-Chip model provides an advanced platform to study human lung function, offering a more accurate and predictive approach to investigating respiratory diseases and…
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Dry Powder Exposure of Air-Liquid Interface (ALI) Cell Cultures: VITROCELL PowderX System
The VITROCELL PowderX Exposure System is the ideal tool for aerosolisation of small quantities of dry powders and particle deposition on cells cultured in 12- or 24-well sized inserts. It is designed for evaluation of pharmaceutical compounds and toxicological evaluation of particles and fibres. Small powder samples of 1–100 mg are positioned in the quick-lock loading system. Subsequent aerosolisation of the powder takes place under high pressure by a unique jet system. The resulting shear forces facilitate deagglomeration for homogeneous dispersion into the expansion chamber. Final deposition takes place via gravimetric settling. The height of the expansion chamber can be varied in three different steps according to the behaviour and…
