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Dynamic Spirit of Innovation: 2nd MPS World Summit in Berlin
The 2023 World Summit for microphysiological systems (MPS) had a record attendence with over 1,200 participants from all over the world. The increase of attendees from 700 at the 2022 MPS Meeting in New Orleans showed the dynamics in this emerging field. 196 speakers reported on their research using organs-on-chip. The conference started with a very successful Educational Workshop where VITROCELL explained the exposure to the AlveoliX AX12 lung-on-chip using the exposure system Cloud Alpha AlveoliX AX12. Clémentine Richter from the Helmholtz Institute for Pharmaceutical Research Saarland, Saarbrücken, Germany presented her poster on alveolar inflammation illustrating human drug response using the Cloud Alpha AlveoliX AX12 (See Poster) The exhibition gave…
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VITROCELL® Remote Assist Support
VITROCELL in-vitro-Expositionssysteme werden spezifisch nach Kundenwunsch gefertigt. Unsere Kunden aus Forschung & Entwicklung haben meist sehr komplexe Anforderungen an die Anlage. Daher werden Produktschulungen sowie Service & Support von qualifizierten VITROCELL Technikern durchgeführt. Für VITROCELL Anwender auf der ganzen Welt möchten wir stets eine schnelle Reaktion und Problemlösung ermöglichen. Live Assistance mit Augmented Reality Eine enorme Erleichterung bietet hier der Einsatz von Augmented Reality. Bei VITROCELL setzen wir auf die HoloLens 2 von Microsoft. Sie erlaubt unserem Support, in Echtzeit passgenaue Anleitungen zu geben. Das Sichtfeld des Anwenders wird auf den Monitor des Technikers übertragen. Dieser kann so eine Schulung der Anlage aus der Ferne durchführen, oder Möglichkeiten zur…
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VITROCELL® AES for toxicity testing of airborne particles
DOI:10.3791/61210 Hedwig M. Braakhuis1, Ruiwen He1,2, Rob J. Vandebriel1, Eric R. Gremmer1, Edwin Zwart1, Jolanda P. Vermeulen1, Paul Fokkens1, John Boere1, Ilse Gosens1, Flemming R. Cassee1,2 1National Institute for Public Health and the Environment (RIVM) 2Institute for Risk Assessment Sciences (IRAS) This article provides a method for culturing and exposing the human bronchial epithelial cell line Calu-37 at the Air-liquid Interface that mimics realistic, repeated inhalation exposure conditions that can be used for toxicity testing. By applying a continuous airflow using the Automated Exposure System, the cell model can be exposed to a low concentration of particles over a longer time period, reflecting realistic exposure conditions. Characteristics of both the…
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New VITROCELL® Millicell Holder
The revolutionary new holder system enables for the use of standing inserts in all modules of the VITROCELL® 12 Series for 12-well sized inserts. As an additional advantage, the media compartment is sealed towards the aerosol exposure head to avoid contact of the test substance with the cell culture media. VITROCELL® Holder system set: Insert holder with o-ring Adaptor Insert mounting tool Holder removal tool Mounting procedure: Place the adaptor in the exposure module. Then mount the insert in the insert holder using the insert mounting tool. Place the insert holder with the mounted insert into the adaptor. Make sure that no air bubbles are situated under the membrane: add…
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The New VITROCELL® RH/T-Controller
The VITROCELL® RH/T-Controller system was designed to measure temperature and relative humidity in numerous applications at high precision. It can be fitted to humidification systems, aerosol ducts and climatic chambers. In cell exposure, relative humidity is a key factor for cell viability – this is even more important at longer exposure durations. With the new RH/T Controller set VITROCELL® has brought the technology from the Automated Stations to custom configurations. The sensors are availabe in 2 insertion lengths ( 35 mm and 65 mm). They come calibrated with a factory certificate. Re-calibration can be performed using the VITROCELL® Monitor software. VITROCELL® Monitor Software The VITROCELL® RH/T-Controller can be operated as…
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VITROCELL® Cloud Alpha Family
The VITROCELL® Cloud α series for automated exposure of cell cultures has been enlarged and now comprises the Cloud Alpha 6, Cloud Alpha 12, Cloud Alpha 96 and Cloud Alpha MAX. They represent an optimal solution for everyday cell exposure experiments at the Air/Liquid Interface using 6-well, 12-well, 24-well or 96-sized inserts. The product solutions combine reliable exposure of cell cultures from the respiratory tract with ease of use. This video showcases available product configurations. Über die VITROCELL Systems GmbH Advanced in vitro exposure systems Firmenkontakt und Herausgeber der Meldung: VITROCELL Systems GmbH Fabrik Sonntag 3 79183 Waldkirch Telefon: +49 (7681) 4977950 http://www.vitrocell.com Ansprechpartner: Tobias Krebs Managing Director Telefon: +49 (7681)…
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VITROCELL® 12/12 now available with Climatic Chamber
The VITROCELL® 12/12 module system has been designed to facilitate the exposure of mammalian cell cultures to airborne substances such as gases, complex mixtures, nanoparticles and fibers. It features a throughput of 3 dilution steps @ 3 replicates and 1 clean air control at 3 replicates. In order to optimize the exposure for liquid aerosols and to maximize the performance of humidified air supply it is now also available in a user-friendly climatic chamber. Exposure at the Air/Liquid Interface In response to the scientific need to expose in physiologically relevant conditions, the VITROCELL® exposure devices have been specifically designed to enable direct exposure of mammalian cells or tissue at the Air/Liquid…
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New Video: VITROCELL® Cloud α – for Aerosol Research and Cell Exposure at the Air/Liquid Interface (ALI)
The VITROCELL® Cloud Alpha series is our newest innovation and presents a great leap forward in automated exposure of cell cultures. It combines reliable exposure of cell cultures from the respiratory tract with ease of use. This series is our new take on the well-known and frequently published VITROCELL® Cloud systems (6-, 12- and 24-well). Its functionality enables fully automated processes with an all-in-one control unit. Everyday experiments at the air/liquid interface have never been easier. The Cloud system is suitable for nebulization of solutions and suspensions. Possible fields of application are screening of inhaled drugs, virus research toxicity testing of inhaled substances such as chemicals or nanoparticles. In response…
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VITROCELL® Shisha Testing System for Cell Cultures
. Background Emissions of water pipe tobacco can now be tested by in vitro exposure in a reliable and user-friendly setup. The novel Shisha Testing Device can be combined with any VITROCELL® Exposure System. The same setup can also be expanded for chemical analysis of Shisha emissions. Solution The Shisha Testing System consists of the following components: 1. Shisha Testing Device 2. VC 1 Smoking Machine 3. Cell Culture Exposure System 1. Shisha Testing Device The device follows the specifications of ISO 22486. The system can be operated with charcoal or via electrical heating. The water pipe tobacco holder is made of ceramics and holds approx. 25 ml of tobacco. The electrical…
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VITROCELL® Cloud Alpha 96
The VITROCELL® Cloud Alpha 96 is our newest innovation and presents a great leap forward in automated exposure of cell cultures. It combines high throughput testing with ease of use. The development is based on the well-known and frequently published VITROCELL® Cloud formats (6-, 12- and 24-well). It’s functionality enables fully automated processes with an all-in-one control unit. Everyday experiments at the air/liquid interface have never been easier. The new Cloud Alpha 96 series was developed as a result of numerous customer requests and is now capable to expose mammalian cell cultures in Corning ® HTS Transwell ® 96-Well Permeable Support Systems. The Cloud system is suitable for nebulization of…
